Bio

QUALIFICATION:  Biochemistry Ph.D with >9 years of industrial experience in biopharmaceutical company  In-depth understanding of downstream process operations (chromatography and filtration) of biologics  A proven track record of purifying multiple modalities of biologics drugs  Process development with high-throughput process development and statistical design of experiments (DoE)  Process characterization and technology transfer into industrial GMP environment  Authoring CMC documents for IND and BLA regulatory filings  Managing/mentoring scientists in a laboratory setting SKILLS:  Nucleic acid chemistry, enzymatic reactions, PCR, and plasmid processing  in vitro transcription and mRNA purification technologies  ÄKTA systems, TECAN system, and PendoTECH System  Affinity, ionic exchange, hydrophobic, and mixed mode chromatography  Depth filtration, microfiltration, nanofiltration, sterile filtration, and ultrafiltration  SEC, PAGE, DLS, DSF/DSC, ITC, ELISA, Northern/Southern/Western blots  JMP, @RISK, Geneious, RNA structure, PyMol, VectorNTI, Spotfire, ImageQuant, Image Lab