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Harsha Gunawardena

Principal Scientist

Johnson & Johnson

Country or State

United States

Bio

Analytical chemist/technologist with a broad background in mass spectrometry, chromatography, electrophoresis, instrumentation and method development, automation, MS based bioinformatics, in-vivo and in-vitro biochemical and cell-based assays, A proven track record of utilizing a variety of sample analysis techniques in protein science and analytical instrumentation to solve challenging scientific problems in biology, chemistry, and medicine as exemplified by publications found in Google Scholar and Research Gate. Supported a diverse portfolio of projects in areas of immunology, oncology, bacteriology, redox biology, basic chemistry, analytical method development, epigenetics, and characterization of protein biotherapeutics See representative academic publications in Google Scholar and Research Gate emphasizing large-scale shotgun proteomics methods applied in various discovery biology projects. Specialties: 1. Develop, design and implement advanced mass spectrometry devices: RF electronics, ion trajectory simulations, ion manipulation and gas-phase ion chemistry schemes that enable novel applications in protein analysis 2. Generate predictive models using Ab initio and ion trajectory simulations to understand gas-phase reaction kinetics and dynamics 3. Experienced with implementing hyphenation and automation techniques: LC-MS, 2D-LC-MS, CE-MS, RePlay and device automation to enable protein characterization and large-scale proteomics projects 4. Analysis, integration and visualization of large-scale shotgun proteomics data, generate mass spectrometry data for multi-omics and pan-omics experiments in both academia and biotechnolgy settings 5. In-depth characterization of mAbs, DARTs, Duobodies, ADCs, and fusion proteins in biophrama settings to support programs jn lead discovery, developability assessment and clone selection. 6. Implement disruptive technologies to accelerate discovery research in biopharma

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Current Position

Principal Scientist at Johnson & Johnson

Degrees

Business Administration and Management, General

Skills